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Caring for the Critically Ill Patient

Explore JAMA’s influential critical care medicine series, including new guidelines, important clinical trials, and more on topics such as sepsis and respiratory failure and ventilation.

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JAMA

Original Investigation

Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Yonathan Freund, MD, PhD, Damien Viglino, MD, PhD et al.

Editorial

The Value of Not Intubating Comatose Patients With Acute Poisoning

Zaffer Qasim, MD, Jeanmarie Perrone, MD et al.

Original Investigation

Sigh Ventilation in Patients With Trauma

Richard K. Albert, MD, Gregory J. Jurkovich, MD et al.

Editorial

Sigh Breaths for Trauma Patients Receiving Mechanical Ventilation

Giacomo Bellani, MD, PhD, Antonio Pesenti, MD

Medical News & Perspectives

Can Predictive AI Improve Early Sepsis Detection?

Rebecca Voelker, MSJ, Yulin Hswen, ScD, MPH

Medical News in Brief

Convalescent Plasma Lowered Risk of Death in COVID-19 ARDS

Emily Harris

The Arts and Medicine

The Autumn Ghost —The Danish Polio Epidemic of 1952 and the Birth of Intensive Care Medicine

David Oshinsky, PhD

A Piece of My Mind

“Five Minutes”

Elizabeth Crowe, MD

Special Communication

Red Blood Cell Transfusion—AABB Guidelines

Jeffrey L. Carson, MD, Simon J. Stanworth, MD, DPhil et al.

Original Investigation

Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury

Ross Davenport, PhD, Nicola Curry, MD et al.

Original Investigation

Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta

Jan O. Jansen, PhD, Jemma Hudson, PhD et al.

Original Investigation

Small-Volume Blood Collection Tubes to Reduce Transfusions in Intensive Care

Deborah M. Siegal, MD, Emilie P. Belley-Côté, MD, PhD et al.

Original Investigation

Red Blood Cell Transfusion in the Intensive Care Unit

Senta Jorinde Raasveld, MD, Sanne de Bruin, MD, PhD et al.

JAMA Insights

Blood and Its Components

Claudia S. Cohn, MD, PhD, Beth H. Shaz, MD, MBA

Editorial

Blood, Bleeding, and Transfusion—A Theme Issue

Christopher W. Seymour, MD, MSc

Original Investigation

Intravenous Vitamin C for Patients Hospitalized With COVID-19

The LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators

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JAMA NETWORK

Original Investigation

Patient Outcomes After Long-Term Acute Care Hospital Closures

Anica C. Law, MD, MS, Nicholas A. Bosch, MD, MSc et al.

JAMA Network Open |

Original Investigation

Remote Monitoring for Seizures During Therapeutic Hypothermia in Neonates With HIE

Gabriel Fernando Todeschi Variane, MD, PhD, Alex Dahlen, PhD et al.

JAMA Network Open |

Original Investigation

Comorbid Prolonged Grief, PTSD, and Depression Trajectories for Bereaved Family Surrogates

Fur-Hsing Wen, PhD, Holly G. Prigerson, PhD et al.

JAMA Network Open |

Original Investigation

Correlates of Risk for Disinhibited Behaviors in the Million Veteran Program Cohort

Peter B. Barr, PhD, Tim B. Bigdeli, PhD et al.

JAMA Psychiatry |

Invited Commentary

Placental Perfusion Rather Than Transfusion: Key to Umbilical Cord Management?

Calum T. Roberts, PhD

JAMA Network Open |

Original Investigation

Extrauterine Placental Perfusion and Oxygenation in Infants With Very Low Birth Weight

Benjamin Kuehne, MD, Berthold Grüttner, MD et al.

JAMA Network Open |

Original Investigation

Use of Dexmedetomidine and Opioids in Hospitalized Preterm Infants

Samantha Curtis, MD, Ryan Kilpatrick, MD et al.

JAMA Network Open |

Research Letter

Diagnostic Stewardship Program to Reduce Blood Culture Rates Among Critically Ill Children

Charlotte Z. Woods-Hill, MD, MSHP, Danielle W. Koontz, MA, MS et al.

JAMA Pediatrics |

Original Investigation

Outcomes Following Lung Transplant for COVID-19–Related Complications in the US

Panagiotis Tasoudis, MD, Leonard J. Lobo, MD et al.

JAMA Surgery |

Invited Commentary

Lung Transplant for Acute Respiratory Distress Syndrome

Emily Cerier, MD, Ankit Bharat, MD

JAMA Surgery |

Original Investigation

Midline Compared With Peripheral Intravenous Catheters for Therapy of 4 Days of Longer in Pediatric Patients

Tricia M. Kleidon, RN, MNursPrac, Victoria Gibson, RN et al.

JAMA Pediatrics |

Original Investigation

S aureus Infections in Patients With and Without Preoperative Colonization

Darren P. R. Troeman, MD, Derek Hazard, MSc et al.

JAMA Network Open |

Original Investigation

Generation of Aerosols by Noninvasive Respiratory Support Modalities

Madeline X. Zhang, MSc, Thijs A. Lilien, MD et al.

JAMA Network Open |

Invited Commentary

Computer-Supervised EVD Raises Safety Questions in ICU Care of IVH

Daniel F. Hanley, MD, Wendy C. Ziai, MD, MPH et al.

JAMA Network Open |

Original Investigation

Criteria for Identifying Individuals at High Risk of Progression to Severe AUD

Alex P. Miller, PhD, Sally I-Chun Kuo, PhD et al.

JAMA Network Open |

Original Investigation

Intraventricular Lavage vs External Ventricular Drainage for Intraventricular Hemorrhage

Mette Haldrup, MD, Mads Rasmussen, MD, PhD et al.

JAMA Network Open |
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