New Online

This study assesses what hospital characteristics, including hospital participation in payment and delivery reform, are associated with activities related to health-related social needs.

Generative artificial intelligence (AI) has been touted as a potential innovation for greater diagnostic accuracy and clinical efficiency in health care, but whether generative AI will deliver on this promise or fall to the “productivity paradox” is examined in this Special Communication.

This Viewpoint argues that although “food is medicine” programs may help some patients prevent diet-related diseases, changing food industry behavior and ensuring that existing nutrition assistance programs are accessible and health-promoting are better strategies to make a difference.

This Viewpoint discusses a recent executive order by US President Joe Biden about the development and implementation of AI, including the role of government vs the private sector and how the order may affect health care.

This clinical trial compares the efficacy of intubation withholding vs routine practice on clinical outcomes of comatose patients with acute poisoning and a Glasgow Coma Scale score less than 9.

This Medical News article discusses a new study that identified how business have pivoted marketing of unapproved stem cell and exosome products from COVID-19 to long COVID.

This Medical News article discusses why physicians don’t stop prescribing drugs that may no longer be needed.

This Viewpoint discusses ways in which clinical research directly and indirectly contributes to anthropogenic climate change, highlights the need for increased scientific soundness and value in research, and calls for the development of tools for calculating the environmental impact of studies and a strategy for ensuring that research does not compromise the rights and welfare of nonparticipants and future generations.

In this narrative medicine essay, a retired family physician recalls sitting with her mother in the final minutes of her life after the ventilator has been removed.

This Insights in the Women’s Health series describes perinatal depression (occurring prepregnancy through postpartum periods) and new recommendations and treatment guidelines for this condition.

This Viewpoint explains the genetic association between Alzheimer disease and Down syndrome and the negative impact of excluding people with Down syndrome from clinical trials on treatment for Alzheimer disease.

This Medical News article discusses late-breaking science and other clinical highlights from the American Heart Association’s Scientific Sessions meeting.

This study assesses whether learning gains associated with full-day preschool were sustained through third grade by analyzing achievement scores and need for remediation.

This Viewpoint reviews the state of alternative payment models (APMs) applied to pregnancy and proposes clinical and policy objectives that could guide model design going forward.

This Viewpoint discusses the use of privacy-preserving record linkage, a token-based record linkage system, as a promising avenue for building a data infrastructure system that bridges isolated data.

This Viewpoint argues for an expansion of paid family leave policies to include eldercare as a way to support the well-being of faculty members, retain physicians, and promote gender equity in academic medicine.

An patient with a history of bullous pemphigoid treated with oral prednisolone presented with multiple round, dark brown to violaceous-colored firm nodules on the right leg and 2 nodular masses with hemorrhagic crusts on the right foot. Complete blood cell count and creatinine and liver function test results were normal, and results of HIV antibody testing were negative. What is the diagnosis and what would you do next?

This randomized study examines the effect of higher-dose fluvoxamine on time to sustained recovery from mild to moderate COVID-19 or progression to severe disease in nonhospitalized adults.

In this narrative medicine essay, a family medicine physician’s experience while undergoing a breast biopsy inspires her to build trust with her patients by listening and counseling more.

This JAMA Patient Page describes diabetic foot ulcers and their evaluation and treatment.

This study uses commercial claims data to assess whether quaternary hospitals charge higher prices for common, unspecialized services also offered by nonquaternary hospitals.

This Viewpoint considers AI’s limits in solving the medical billing quagmire and argues that standardizing health insurance claim forms and simplifying billing must occur before AI can shoulder the load.

This article in the Women’s Health series discusses recent increases in US maternal death rates, disparities in rates by race and ethnicity, poor cardiovascular health (CVH) as one of the multifactorial causes, and clinical approaches to assessing and treating poor CVH postpartum.

In this Medical News interview, Stanford Health Care’s chief data scientist Nigam Shah, MBBS, PhD, discusses ways to train and evaluate artificial intelligence models for use in health care.

This Medical News article discusses Wegovy, Ozempic, and other GLP-1 receptor agonists used for weight management and type 2 diabetes.

This Medical News article discusses the November 8 US Food and Drug Administration approval of the drug tirzepatide for chronic weight management in people with obesity or overweight with weight-related conditions.

This study examines all patents associated with biologic litigation to understand how manufacturers use ancillary product patents to delay biosimilar market entry.

This study examines the frequency of drug patent invalidations based on inequitable conduct.

This randomized clinical trial compares a single dose of lepodisiran vs placebo to assess the safety, tolerability, pharmacokinetics, and effects on lipoprotein(a) concentrations in adults without cardiovascular disease and with lipoprotein(a) serum concentrations of 75 nmol/L or greater at baseline.

This crossover trial assesses whether high-sodium and low-sodium dietary interventions affect 24-hour ambulatory blood pressure measures among middle-aged to elderly adults with normotension, controlled hypertension, uncontrolled hypertension, or untreated hypertension.

This randomized clinical trial examines the safety of the exclusion of aspirin as part of an antithrombotic regimen including a vitamin K antagonist with a fully magnetically levitated left ventricular assist device.

This study quantifies the change in travel times for military service personnel to abortion facilities following the US Supreme Court Dobbs decision and estimates the cost of an abortion-related travel reimbursement policy.

In this narrative medicine essay, a pediatric oncologist grapples with the emotions of loss and guilt while attending the memorial service of her 8-year-old patient.

This JAMA Patient Page describes the types and symptoms of pituitary adenomas and their diagnosis and treatment.

This review summarizes evidence regarding Black race and inequities in outcomes of hepatitis C virus (HCV) infection because of the high prevalence and absolute number of annual HCV-related deaths in Black populations relative to other racial and ethnic minority groups.

This review summarizes current evidence regarding diagnosis and treatment of hepatitis D virus.

In this Viewpoint, the author examines whether health care professionals have any responsibilities to speak out about the conflict in the Middle East.

This Medical News article discusses a recent American Heart Association presidential advisory on CKM syndrome that lays the groundwork for a new cardiovascular disease risk calculator.

This Medical News article is an interview with infectious disease physician Heather Yun, MD, cochair of this year’s Infectious Diseases Week meeting in Boston.

This Viewpoint offers insight into the health effects of the recent fires in Hawaiʻi and what culturally conscious approaches are needed to ensure the health of Native Hawaiians going forward.

This Viewpoint examines disparities and inequalities regarding life expectancy in American Indian and Alaska Native populations and what can be done to address them.

This JAMA Patient Page describes the types of topical nonprescription pain medications and tips for using them.