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November 27, 2023
Inside Story

The Hockey Stick

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6038

This essay describes the author’s experience in interacting with a patient diagnosed with a serious illness and how focusing on the patient’s interests and making them happy was an example of a low-tech, high-touch intervention.

Original Investigation

Effect of Personalized Risk-Reduction Strategies on Cognition and Dementia Risk Profile Among Older Adults: The SMARRT Randomized Clinical Trial

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6279

This randomized clinical trial aims to determine if a personalized, multidomain risk-reduction intervention improves cognition and dementia risk profile among adults 70 years and older.

Health Care Policy and Law

Cost of Exempting Sole Orphan Drugs From Medicare Negotiation

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6293

This cross-sectional study examines the costs of the exemption from Medicare price negotiation under the Inflation Reduction Act (IRA) for drugs approved solely for the treatment of a single rare disease.

Research Letter

Association of Smoking Cessation and Cardiovascular, Cancer, and Respiratory Mortality

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6419

This study examines the association between years since quitting smoking and mortality in the US from 1997 to 2018.

Guide to Statistics and Methods

Population Weighting in Statistical Analysis

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6300

This Guide to Statistics and Methods provides an overview of weighted analyses of population-based survey, which can help achieve statistically valid, representative population-based findings.

Challenges in Clinical Electrocardiography

A Wide Wide QRS

Abstract Full Text
has active quiz
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.4846

This case report describes a patient in their 70s with shortness of breath and generalized weakness and a history of coronary artery bypass surgery, ischemic cardiomyopathy, a dual-chamber defibrillator, paroxysmal atrial fibrillation, and kidney failure while undergoing hemodialysis.

Comment & Response

Discrepancies in Estimating Excess Death by Political Party Affiliation During the COVID-19 Pandemic

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.5831

Discrepancies in Estimating Excess Death by Political Party Affiliation During the COVID-19 Pandemic

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6074

Discrepancies in Estimating Excess Death by Political Party Affiliation During the COVID-19 Pandemic—Reply

Abstract Full Text
JAMA Intern Med. Published online November 27, 2023. doi:10.1001/jamainternmed.2023.6068
November 20, 2023
Viewpoint

One Size Fits All—An Underappreciated Health Inequity

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.6035

This Viewpoint discusses why health priorities–tailored care, rather than the one-size-fits-all approach, is beneficial for marginalized individuals.

Original Investigation

Risk of Bleeding Following Non–Vitamin K Antagonist Oral Anticoagulant Use in Patients With Acute Ischemic Stroke Treated With Alteplase

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.6160

This Taiwanese cohort study evaluates the risk of bleeding and mortality after alteplase treatment for patients with acute ischemic stroke treated with non–vitamin K antagonist oral anticoagulants (NOACs) vs not treated with NOACs.

Health Care Policy and Law

Provenance and Clinical Benefit of Medicines Introduced to the French Market, 2008 to 2018

Abstract Full Text
open access
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.6249

This cross-sectional study examines the provenance and clinical benefit of medicines that entered the French market between 2008 and 2018 using the Prescrire and Haute Autorité de Santé grading systems.

Invited Commentary

Therapeutic Benefit From New Drugs From Pharmaceutical Companies

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.6256

Why Some Patients Overpay for Specialty Generic Drugs

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.6071
Research Letter

Medicare Part D Payments for Generic Imatinib From 2017 to 2023

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.3932

This cross-sectional study compares pharmacy acquisition costs and point-of-sale prices for generic imatinib under Medicare Part D from 2017 to 2023.

Challenges in Clinical Electrocardiography

Repeatedly Malignant ST-Segment Elevation

Abstract Full Text
has active quiz
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.4841

This case report describes a patient in their early 50s who presented with epigastric pain and jaundice and had significantly decreased heart rate after admission.

Comment & Response

Corrections to a Meta-Analysis of Oseltamivir Use in Preventing Hospitalization for Influenza

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.4708

Oseltamivir May or May Not Reduce Hospitalizations

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.4711

Oseltamivir May or May Not Reduce Hospitalizations

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.4720

Oseltamivir May or May Not Reduce Hospitalizations—Reply

Abstract Full Text
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.5769
Correction

Error in Size of Total Population

Abstract Full Text
free access
JAMA Intern Med. Published online November 20, 2023. doi:10.1001/jamainternmed.2023.4905
November 13, 2023
Viewpoint

Physician Work Environment and Well-Being

Giving Patients the Focused Attention They Deserve

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5987

This viewpoint discusses the need for physicians to give focused attention to patients and the challenges that prevent them from doing so and suggests goals to create conditions that ensure that physicians are fully present during patient visits.

Inside Story

Spielberg’s Secret

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5901

This essay describes how a podcast inspired a physician’s new approach to complimenting patients and colleagues and the benefits gained.

Invited Commentary

Health Disinformation—Gaining Strength, Becoming Infinite

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5946
Special Communication

Health Disinformation Use Case Highlighting the Urgent Need for Artificial Intelligence Vigilance: Weapons of Mass Disinformation

Abstract Full Text
has active quiz
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5947

This study examines whether artificial intelligence (AI) models can be manipulated for the generation of targeted health disinformation regarding vaccines and vaping.

Research Letter

Shift From Smoking Cigarettes to Vaping Nicotine in Young Adults

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5239

This survey study assesses trends in nicotine use among young adults in the US between 2013 and 2021.

Widening Gender Gap in Life Expectancy in the US, 2010-2021

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.6041

This cross-sectional study systematically examines the contributions of COVID-19 and other underlying causes of death to the widened gender life expectancy gap from 2010 to 2021.

Challenges in Clinical Electrocardiography

Acute Myocardial Infarction Revealed by an Escape Rhythm in a Patient With Failed Sgarbossa Criteria

Abstract Full Text
has active quiz
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.3632

This case report describes a man in his 80s with a medical history of essential hypertension who presented to the emergency department with sudden onset epigastric pain.

JAMA Internal Medicine Patient Page

I Am Worried I Have Sciatica—What Do I Need to Know?

Abstract Full Text
free access
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5990

This JAMA Internal Medicine Patient Page reviews sciatica, its symptoms, and treatment options for those who have it.

Comment & Response

Unusual Tachycardia After Cocaine Use

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5756

Unusual Tachycardia After Cocaine Use—Reply

Abstract Full Text
JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5759
November 6, 2023
Inside Story

Less Is More

Talking About Dying

Abstract Full Text
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5843

This essay describes a palliative medicine physician’s experience with a dying patient and reflections on life.

Original Investigation

Overnight Stay in the Emergency Department and Mortality in Older Patients

Abstract Full Text
has audio
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5961

This French cohort study evaluates in-hospital mortality and adverse effects among older adults (≥75 years) who waited overnight in the emergency department for a bed in a hospital ward.

The Natural History of Disability and Caregiving Before and After Long-Term Care Entry

Abstract Full Text
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5427

This cohort study describes disability and caregiving before and after long-term care facility entry, comparing nursing home, assisted living, and independent living entrants.

Invited Commentary

The Risks of Being in Limbo in the Emergency Department

Abstract Full Text
has audio
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5953

Care Demands Ahead of Transitioning Into Residential Care—A Window Into Family Caregiving at Home

Abstract Full Text
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5490
Challenges in Clinical Electrocardiography

The Tip of the Iceberg—Concealing of Advanced Conduction Abnormality

Abstract Full Text
has active quiz
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.3627

This case report describes a patient in their 80s who presented with dyspnea and syncope during exercise and a history of essential hypertension and Parkinson disease.

Comment & Response

Nonfunctional Adrenal Adenomas and Increased Risk of Mortality

Abstract Full Text
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5692

Nonfunctional Adrenal Adenomas and Increased Risk of Mortality

Abstract Full Text
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5695

Nonfunctional Adrenal Adenomas and Increased Risk of Mortality—Reply

Abstract Full Text
JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5698
November 3, 2023
Original Investigation

Effect of a Novel Multicomponent Intervention to Improve Patient Access to Kidney Transplant and Living Kidney Donation: The EnAKT LKD Cluster Randomized Clinical Trial

Abstract Full Text
open access has multimedia
JAMA Intern Med. Published online November 3, 2023. doi:10.1001/jamainternmed.2023.5802

This randomized clinical trial evaluates the effect of implementing a novel multicomponent intervention designed to target several barriers that prevent eligible patients from completing key steps toward receiving a kidney transplant.

Invited Commentary

Solving the Kidney Transplant Conundrum Through Systems Thinking

Abstract Full Text
JAMA Intern Med. Published online November 3, 2023. doi:10.1001/jamainternmed.2023.5818
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